Canle iónica regulada por voltaxe: Diferenzas entre revisións

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=== Canles de calcio (Ca<sup href="Sodium_channel#Voltage-gated">2+</sup>) ===
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With sixteen different identified genes for human calcium channels, this type of channel differs in function between cell types. [[Voltage-dependent calcium channel|Ca<sup>2+</sup> channels]] produce [[action potential]]s similarly to Na<sup>+</sup> channels in some neurons. They also play a role in [[exocytosis|neurotransmitter release]] in [[chemical synapse|pre-synaptic]] nerve endings. In most cells, Ca<sup>2+</sup> channels regulate a wide variety of biochemical processes due to their role in controlling intracellular Ca<sup>2+</sup> concentrations.<ref name="Jiang_2002" />
 
Identificaron 16 xenes das canles de calcio humano, este tipo de canles difiren na súa función nos distintos tipos celulares. As [[canle de calcio dependente de voltaxe|canles de Ca<sup>2+</sup>]] producen [[potencial de acción|potenciais de acción]] similares ás das canles de Na<sup>+</sup> nalgunhas neuronas. Tamén xogan un papel na [[exocitose|liberación de neurotransmisores]] nas terminacións nerviosas [[sinapse químicae|presináptica]]. Na maioría das células, as canles de Ca<sup>2+</sup> regulan unha ampla variedade de procesos bioquímicos debido ao seu papel no control das concentracións intracelulares de Ca<sup>2+</sup>.<ref name="Jiang_2002" />
=== Canles de potasio (K<sup>+</sup>) ===
 
=== Canles de potasio (K<sup>+</sup>) ===
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[[Voltage-gated potassium channel|Potassium channels]] are the largest and most diverse class of voltage-gated channels, with over 100 encoding human genes. These types of channels differ significantly in their gating properties; some inactivating extremely slowly and others inactivating extremely quickly. This difference in activation time influences the duration and rate of action potential firing, which has a significant effect on electrical conduction along an axon as well as synaptic transmission. Potassium channels differ in structure from the other channels in that they contain four separate polypeptide subunits, while the other channels contain four homologous domain but on a single polypeptide unit.<ref name="Sands_2005" />