Factor de crecemento de hepatocitos: Diferenzas entre revisións

[[Dihexa]] é unha [[pequena molécula]] oralmente activa e penetrante centralmente que se une directamente ao HGF e potencia a súa capacidade de activar o seu receptor, c-Met.<ref name="BenoistKawas2014">{{cite journal | vauthors = Benoist CC, Kawas LH, Zhu M, Tyson KA, Stillmaker L, Appleyard SM, Wright JW, Wayman GA, Harding JW | title = The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 351 | issue = 2 | pages = 390–402 | date = November 2014 | pmid = 25187433 | pmc = 4201273 | doi = 10.1124/jpet.114.218735 }}</ref> É un forte indutor da [[neuroxénese]] e está sendo estudadoestudada para a súa posible aplicación no tratamento da [[enfermidade de Alzheimer]] e a de [[enfermiddeenfermidade de Parkinson|Parkinson]].<ref name="pmid25649658">{{cite journal | vauthors = Wright JW, Harding JW | title = The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease | journal = Journal of Alzheimer's Disease | volume = 45 | issue = 4 | pages = 985–1000 | year = 2015 | pmid = 25649658 | doi = 10.3233/JAD-142814 }}</ref><ref name="WrightKawas2015">{{cite journal | vauthors = Wright JW, Kawas LH, Harding JW | title = The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases | journal = Progress in Neurobiology | volume = 125 | pages = 26–46 | date = February 2015 | pmid = 25455861 | doi = 10.1016/j.pneurobio.2014.11.004 }}</ref>