Factor de crecemento de hepatocitos: Diferenzas entre revisións

Contido eliminado Contido engadido
Miguelferig (conversa | contribucións)
Miguelferig (conversa | contribucións)
Liña 51:
 
== Farmacocinética ==
O HGF exóxeno administrado por [[inxección intravenosa]] é eliminado rapidamente dda circulación polo [[fígado]], e ten unha [[vida media]] de aproximadamente 4 minutos.<ref name="Yang2001">{{cite journal | vauthors = Yang J, Chen S, Huang L, Michalopoulos GK, Liu Y | title = Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth | journal = Hepatology | volume = 33 | issue = 4 | pages = 848–59 | date = April 2001 | pmid = 11283849 | pmc = 1821076 | doi = 10.1053/jhep.2001.23438 }}</ref><ref name="pmid8450646">{{cite journal | vauthors = Appasamy R, Tanabe M, Murase N, Zarnegar R, Venkataramanan R, Van Thiel DH, Michalopoulos GK | title = Hepatocyte growth factor, blood clearance, organ uptake, and biliary excretion in normal and partially hepatectomized rats | journal = Laboratory Investigation; A Journal of Technical Methods and Pathology | volume = 68 | issue = 3 | pages = 270–6 | date = March 1993 | pmid = 8450646 | doi = }}</ref><ref name="KatoLiu1994">{{cite journal | vauthors = Kato Y, Liu KX, Nakamura T, Sugiyama Y | title = Heparin-hepatocyte growth factor complex with low plasma clearance and retained hepatocyte proliferating activity | journal = Hepatology | volume = 20 | issue = 2 | pages = 417–24 | date = August 1994 | pmid = 8045504 | doi = 10.1002/hep.1840200223 }}</ref><ref name="YuYao2007">{{cite journal | vauthors = Yu Y, Yao AH, Chen N, Pu LY, Fan Y, Lv L, Sun BC, Li GQ, Wang XH | title = Mesenchymal stem cells over-expressing hepatocyte growth factor improve small-for-size liver grafts regeneration | journal = Molecular Therapy | volume = 15 | issue = 7 | pages = 1382–9 | date = July 2007 | pmid = 17519892 | doi = 10.1038/sj.mt.6300202 }}</ref>
 
== Moduladores ==