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Citotoxicidade: Diferenzas entre revisións

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Liña 23:
 
== Predición ==
 
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Un asunto moi importante é a predición da citotoxicidade dos compostos químicos baseada en
A highly important topic is the prediction of cytotoxicity of chemical compounds based on
previousprevias measurementsmedidas, i.e.é dicir, probas in- silico testing(por computadora).<ref name="Reisfeld2012">{{Cite journal | pmid = 13677480| year = 2003| author1 = Dearden| first1 = J. C.| title = In silico prediction of drug toxicity| journal = Journal of computer-aided molecular design| volume = 17| issue = 2–4| pages = 119–27| doi=10.1023/A:1025361621494}}</ref>
ofPara theseeste methodspropósito hassuxeríronse beenmoitos donemétodos withinde the[[QSAR]] e [[screening virtual]]. Unha comparación independente destes métodos fíxose no contexto do proxecto "Toxicology in the 21st century" project.<ref name="TOX21">"Toxicology in the 21st century Data Challenge" https://tripod.nih.gov/tox21/challenge/leaderboard.jsp</ref>▼
For this purpose many
[[QSAR]] and [[virtual screening]] methods have been suggested. An independent comparison
▲of these methods has been done within the "Toxicology in the 21st century" project.<ref name="TOX21">"Toxicology in the 21st century Data Challenge" https://tripod.nih.gov/tox21/challenge/leaderboard.jsp</ref>
 
== No cancro ==
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[[Chemotherapy]] as a treatment of [[cancer]] often relies on the ability of cytotoxic agents to kill or damage cells which are reproducing; this preferentially targets rapidly dividing cancer cells.<ref>Ramin Zibaseresht, Photoactivated Cytotoxins, University of Canterbury, 2006.</ref><ref>{{cite web|title=Chemotherapy Principles|url=http://www.cancer.org/acs/groups/cid/documents/webcontent/002995-pdf.pdf|publisher=American Cancer Society|accessdate=20 August 2014}}</ref>
 
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