PARP1: Diferenzas entre revisións

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Miguelferig (conversa | contribucións)
Miguelferig (conversa | contribucións)
Liña 69:
 
PARP1 appears to be resveratrol's primary functional target through its interaction with the tyrosyl tRNA synthetase (TyrRS).<ref>{{cite journal | vauthors = Sajish M, Schimmel P | title = A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol | journal = Nature | date = Dec 2014 | pmid = 25533949 | doi = 10.1038/nature14028 | volume=519 | pages=370–3}}</ref>
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== Interaccións ==
 
A PARP1 presenta [[interaccións proteína-proteína|interaccións]] con:
PARP1 has been shown to [[Protein-protein interaction|interact]] with:
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* [[AprataxinAprataxina|APTX]],<ref name=pmid15044383/><ref name="pmid5555565">{{cite journal | vauthors = Morgan HE, Jefferson LS, Wolpert EB, Rannels DE | title = Regulation of protein synthesis in heart muscle. II. Effect of amino acid levels and insulin on ribosomal aggregation | journal = The Journal of Biological Chemistry | volume = 246 | issue = 7 | pages = 2163–70 | date = Apr 1971 | pmid = 5555565 | doi = }}</ref>
* [[MYBL2]]<ref name="pmid10744766">{{cite journal | vauthors = Cervellera MN, Sala A | title = Poly(ADP-ribose) polymerase is a B-MYB coactivator | journal = The Journal of Biological Chemistry | volume = 275 | issue = 14 | pages = 10692–6 | date = Apr 2000 | pmid = 10744766 | doi = 10.1074/jbc.275.14.10692 }}</ref>
* [[RELA]],<ref name="pmid11590148">{{cite journal | vauthors = Hassa PO, Covic M, Hasan S, Imhof R, Hottiger MO | title = The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function | journal = The Journal of Biological Chemistry | volume = 276 | issue = 49 | pages = 45588–97 | date = Dec 2001 | pmid = 11590148 | doi = 10.1074/jbc.M106528200 }}</ref>
Liña 83:
* [[ZNF423]].<ref name="pmid14623329">{{cite journal | vauthors = Ku MC, Stewart S, Hata A | title = Poly(ADP-ribose) polymerase 1 interacts with OAZ and regulates BMP-target genes | journal = Biochemical and Biophysical Research Communications | volume = 311 | issue = 3 | pages = 702–7 | date = Nov 2003 | pmid = 14623329 | doi = 10.1016/j.bbrc.2003.10.053 }}</ref>
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== Notas ==