Triptófano: Diferenzas entre revisións
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Liña 75:
* [[Serotonina]] (un [[neurotransmisor]]), sintetizado pola [[triptófano hidroxilase]].<ref name="pmid6132421">{{Cita publicación periódica | author = Fernstrom JD | title = Role of precursor availability in control of monoamine biosynthesis in brain | journal = Physiol. Rev. | volume = 63 | issue = 2 | pages = 484–546 | year = 1983 | pmid = 6132421 | doi = | issn = | url = http://physrev.physiology.org/cgi/reprint/63/2/484}}</ref><ref name="pmid1704290">{{Cita publicación periódica | author = Schaechter JD, Wurtman RJ | title = Serotonin release varies with brain tryptophan levels | journal = Brain Res. | volume = 532 | issue = 1-2 | pages = 203–10 | year = 1990 | pmid = 1704290 | doi = 10.1016/0006-8993(90)91761-5| url = http://wurtmanlab.mit.edu/publications/pdf/790.pdf}}</ref> A serotonina á súa vez pode converterse en [[melatonina]] (unha [[hormona]]) coa intervención da N-acetiltransferase e a 5-hidroxiindol-O-metiltransferase.<ref name="pmid4391290">{{Cita publicación periódica | author = Wurtman RJ, Anton-Tay F | title = The mammalian pineal as a neuroendocrine transducer | journal = Recent Prog. Horm. Res. | volume = 25 | issue = | pages = 493–522 | year = 1969 | pmid = 4391290 | doi = | issn = | url = http://wurtmanlab.mit.edu/publications/pdf/104.pdf}}</ref>
* [[Niacina]], sintetizada a partir de triptófano vía os intermediatos principais [[kynurenina]] e ácidos quinolínicos.<ref name="pmid14284754">{{Cita publicación periódica | author = Ikeda M, Tsuji H, Nakamura S, Ichiyama A, Nishizuka Y, Hayaishi O | title = Studies on the biosynthesis of nicotinamide adenine dinucleotide. II. A role of picolinic carboxylase in the biosynthesis of nicotinamide adenine dinucleotide from tryptophan in mammals | journal = J. Biol. Chem. | volume = 240 | issue = | pages = 1395–401 | year = 1965 | pmid = 14284754 | doi = | issn = | url = http://www.jbc.org/cgi/reprint/240/3/1395}}</ref>
* [[Auxina]] (unha [[hormona]] vexetal). Cando os [[elemento dos tubos cribosos|elementos dos tubos cribosos]] (células do [[floema]]) sofren [[apoptose]] o triptófano convértese en auxinas.<ref name="pmid18394986">{{Cita publicación periódica | author = Palme K, Nagy F | title = A new gene for auxin synthesis | journal = Cell | volume = 133 | issue = 1 | pages = 31–2 | year = 2008
Os trastornos denominados [[mala absorción de frutosa]] e [[intolerancia á lactosa]] causan unha absorción deficiente de triptófano no intestino, orixinan niveis de triptófano reducidos no sangue <ref>{{Cita publicación periódica |author=Ledochowski M, Widner B, Murr C, Sperner-Unterweger B, Fuchs D |title=Fructose malabsorption is associated with decreased plasma tryptophan |journal=Scand. J. Gastroenterol. |volume=36 |issue=4 |pages=367–71 |year=2001 |pmid=11336160 |doi=10.1080/003655201300051135}}</ref> e depresión.<ref>{{Cita publicación periódica |author=Ledochowski M, Sperner-Unterweger B, Widner B, Fuchs D |title=Fructose malabsorption is associated with early signs of mental depression |journal=Eur. J. Med. Res. |volume=3 |issue=6 |pages=295–8 |year=1998 |pmid=9620891 |doi=}}</ref>
Liña 94:
== Envellecemento ==
Ratas alimentadas con pouco triptófano mostraron niveis sanguíneos reducidos de [[triiodotironina]], o que se suxeriu retarda o proceso de envellecemento.<ref name="pmid625148">{{Cita publicación periódica | author = Ooka H, Segall PE, Timiras PS | title = Neural and endocrine development after chronic tryptophan deficiency in rats: II. Pituitary-thyroid axis | journal = Mech. Ageing Dev. | volume = 7 | issue = 1 | pages = 19–24 | year = 1978
== Notas ==
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