Hormona liberadora da tirotropina: Diferenzas entre revisións

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== Historia ==
 
A secuencia da TRH foi determinada por [[Roger Guillemin]] e [[Andrew V. Schally]] en 1969, que a sintetizaron.<ref name="pmid4982117">{{Cita publicación periódica | author = Boler J, Enzmann F, Folkers K, Bowers CY, Schally AV | title = The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide | journal = Biochem. Biophys. Res. Commun. | volume = 37 | issue = 4 | pages = 705–10 | year = 1969 | pmid = 4982117 | doi = 10.1016/0006-291X(69)90868-7| url = http://linkinghub.elsevier.com/retrieve/pii/0006-291X(69)90868-7}}</ref><ref name="pmid4983502">{{Cita publicación periódica | author = Burgus R, Dunn TF, Desiderio D, Guillemin R | title = [Molecular structure of the hypothalamic hypophysiotropic TRF factor of ovine origin: mass spectrometry demonstration of the PCA-His-Pro-NH2 sequence] | language = French | journal = C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | volume = 269 | issue = 19 | pages = 1870–3 | year = 1969 | pmid = 4983502 | doi = | url = | issn =}}</ref> Ambas as partes insistiron en que os seus laboratorios determinaron a secuencia primeiro.<ref name="isbn0-8039-0993-4">{{cita libro | autor apelidos1= Woolgar, |nome1=Steve; |apelidos2=Latour, |nome2=Bruno|ligazón-autor2=Bruno Latour| título = Laboratory life: the social construction of scientific facts | edition = | language = | editor = Sage Publications - Thousand Oaks | ano = 1979 | origyear = | pages = | capítulo = Chapter 3: The Case of TRF(H) | quote = | isbn = 0-8039-0993-4 | oclc = | doi = | url = | accessdate = }}</ref>
 
Schally e Guillemin compartiron en 1977 o [[premio Nobel de Medicina]] "polos seus descubrimentos sobre a produción de hormona peptídica no cerebro." <ref name="isbn0-8039-0993-4"/><ref name="urlMedicine 1977">{{Cita web | url = http://nobelprize.org/nobel_prizes/medicine/laureates/1977/index.html | title = The Nobel Prize in Physiology or Medicine 1977 | author = | authorlink = | coauthors = | date = | work = | publisher = NobelPrize.org | pages = | language = | archiveurl = | archivedate = | quote = | accessdate = 2009-03-04}}</ref>