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=== Historia ===
 
A secuenciación de escopeta de xenoma completo de pequenos xenomas (de 40004&nbsp;000 a 70007&nbsp;000 pares de bases) foi suxeridosuxerida por primeira vez en 1979.<ref name="Staden" /> O primeiro xenoma secuenciado por secuenciación de escopeta foi o do [[virus do mosaico da coliflor]], publicado en 1981.<ref>{{Cite journal|last=Gardner|first=Richard C.|last2=Howarth|first2=Alan J.|last3=Hahn|first3=Peter|last4=Brown-Luedi|first4=Marianne|last5=Shepherd|first5=Robert J.|last6=Messing|first6=Joachim|date=1981-06-25|title=The complete nucleotide sequence of an infectious clone of cauliflower mosaic virus by M13mp7 shotgun sequencing|url=http://nar.oxfordjournals.org/content/9/12/2871|journal=Nucleic Acids Research|language=en|volume=9|issue=12|pages=2871–2888|doi=10.1093/nar/9.12.2871|issn=0305-1048|pmid=6269062|pmc=326899}}</ref><ref>{{Cite journal|last=Doctrow|first=Brian|date=2016-07-19|title=Profile of Joachim Messing|url=http://www.pnas.org/content/113/29/7935|journal=Proceedings of the National Academy of Sciences|language=en|volume=113|issue=29|pages=7935–7937|doi=10.1073/pnas.1608857113|issn=0027-8424|pmid=27382176|pmc=4961156}}</ref>
 
=== Secuenciación de extremos apareados ===
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