Serotonina: Diferenzas entre revisións

A serotonina libérase no espazo entre as neuronas, e difunde no [[espazo sináptico]] (de >20 µm) para activar os [[receptor 5-HT|receptores 5-HT]] localizados nas [[dendrita]]s, corpos celulares e terminais presinápticas das neuronas adxacentes.

As [[droga psicodélica|drogas psicodélicas]] [[psilocina]]/[[psilocibina]], [[dimetiltriptamina|DMT]], [[mescalina]], e [[LSD]] son [[agonista]]s, principalmente nos receptores [[receptor 5-HT2A|5HT_2A]] e [[receptor 5HT2C|5HT_2C]].<ref name="pmid3127847">{{Cita publicación periódica|author = Titeler M, Lyon RA, Glennon RA|title = Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens|journal = Psychopharmacology (Berl.)|volume = 94|issue = 2|pages = 213–6|year = 1988|pmid = 3127847}}</ref><ref name="isbn3-540-66715-6">{{cita libro|autor = Nichols DE|editor = Baumgarten HG, Gothert M|título = Serotoninergic Neurons and 5-HT Receptors in the CNS|editorial = Springer-Verlag TELOS|location = Santa Clara, CA|ano = 2000|isbn = 3-540-66715-6|capítulo = Role of serotonergic neurons and 5-HT receptors in the action of hallucinogens}}</ref> O [[empatóxeno-entactóxeno]] [[MDMA]] libera serotonina das [[vesícula sináptica|vesículas sinápticas]] das neuronas.<ref name="pmid2880735">{{Cita publicación periódica|author = Johnson MP, Hoffman AJ, Nichols DE|title = Effects of the enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices|journal = Eur. J. Pharmacol.|volume = 132|issue = 2–3|pages = 269–76|year = 1986|pmid = 2880735|doi = 10.1016/0014-2999(86)90615-1}}</ref>