Factor de crecemento de hepatocitos: Diferenzas entre revisións

Contido eliminado Contido engadido
Miguelferig (conversa | contribucións)
Miguelferig (conversa | contribucións)
Liña 48:
-->
=== Niveis de plasma circulantes ===
O [[plasma sanguíneo|plasma]] de pacientes con insuficiencia cardíaca avanzada presenta niveis incrementados de HGF, o cal se correlaciona cun prognóstico negativo e un alto risco de mortalidade.<ref>{{cite journal | vauthors = Richter B, Koller L, Hohensinner PJ, Zorn G, Brekalo M, Berger R, Mörtl D, Maurer G, Pacher R, Huber K, Wojta J, Hülsmann M, Niessner A | title = A multi-biomarker risk score improves prediction of long-term mortality in patients with advanced heart failure | journal = International Journal of Cardiology | volume = 168 | issue = 2 | pages = 1251–7 | date = September 2013 | pmid = 23218577 | doi = 10.1016/j.ijcard.2012.11.052 }}</ref><ref>{{cite journal | vauthors = Rychli K, Richter B, Hohensinner PJ, Kariem Mahdy A, Neuhold S, Zorn G, Berger R, Mörtl D, Huber K, Pacher R, Wojta J, Niessner A, Hülsmann M | title = Hepatocyte growth factor is a strong predictor of mortality in patients with advanced heart failure | journal = Heart | volume = 97 | issue = 14 | pages = 1158–63 | date = July 2011 | pmid = 21572126 | doi = 10.1136/hrt.2010.220228 }}</ref> O HGF circulante foi tamén identificado como marcador de prognóstico de gravidde en pacientes que padecen hipertensxión.<ref name="ReferenceB">{{cite journal | vauthors = Nakamura S, Morishita R, Moriguchi A, Yo Y, Nakamura Y, Hayashi S, Matsumoto K, Matsumoto K, Nakamura T, Higaki J, Ogihara T | title = Hepatocyte growth factor as a potential index of complication in diabetes mellitus | journal = Journal of Hypertension | volume = 16 | issue = 12 Pt 2 | pages = 2019–26 | date = December 1998 | pmid = 9886892 | doi = 10.1291/hypres.22.161 }}</ref><ref name="ReferenceB"/> O HGF circulante tamén se suxeriu como posible [[biomarcador`]] precoz da fase aguda da [inflamación]] intestinal.<ref>{{cite journal | vauthors = Sorour AE, Lönn J, Nakka SS, Nayeri T, Nayeri F | title = Evaluation of hepatocyte growth factor as a local acute phase response marker in the bowel: the clinical impact of a rapid diagnostic test for immediate identification of acute bowel inflammation | journal = Cytokine | volume = 71 | issue = 1 | pages = 8–15 | date = January 2015 | pmid = 25174881 | doi = 10.1016/j.cyto.2014.07.255 }}</ref>
 
== Farmacocinética ==