Diferenzas entre revisións de «Receptor da vitamina D»

(traducido de en:Calcitriol receptor)
 
Experimental studies have shown that the unliganded VDR interacts with regulatory regions in cWnt ([[wnt signaling pathway]]) and [[sonic hedgehog]] target genes and is required for the induction of these pathways during the postnatal hair cycle.<ref name="pmid25180455">{{cite journal | vauthors = Lisse TS, Saini V, Zhao H, Luderer HF, Gori F, Demay MB | title = The Vitamin D Receptor Is Required for Activation of cWnt and Hedgehog Signaling in Keratinocytes | journal = Mol. Endocrinol. | volume = 28 | issue = 10 | pages = 1698–1706 | date = September 2014 | pmid = 25180455 | doi = 10.1210/me.2014-1043 | pmc=4179637}}</ref>
These studies have revealed novel actions of the unliganded VDR in regulating the post-morphogenic hair cycle.
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== Interaccións ==
 
* [[RUNX1T1]],<ref name=pmid12460926/>
* [[SNW1]],<ref name="pmid11514567">{{cite journal | vauthors = Zhang C, Baudino TA, Dowd DR, Tokumaru H, Wang W, MacDonald PN | title = Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription | journal = J. Biol. Chem. | volume = 276 | issue = 44 | pages = 40614–20 | date = November 2001 | pmid = 11514567 | doi = 10.1074/jbc.M106263200 }}</ref><ref name="pmid9632709">{{cite journal | vauthors = Baudino TA, Kraichely DM, Jefcoat SC, Winchester SK, Partridge NC, MacDonald PN | title = Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription | journal = J. Biol. Chem. | volume = 273 | issue = 26 | pages = 16434–41 | date = June 1998 | pmid = 9632709 | doi = 10.1074/jbc.273.26.16434 }}</ref>
* [[STAT1]],<ref name="pmid11909970">{{cite journal | vauthors = Vidal M, Ramana CV, Dusso AS | title = Stat1-Vitamin D Receptor Interactions Antagonize 1,25-Dihydroxyvitamin D Transcriptional Activity and Enhance Stat1-Mediated Transcription | journal = Mol. Cell. Biol. | volume = 22 | issue = 8 | pages = 2777–87 | date = April 2002 | pmid = 11909970 | pmc = 133712 | doi = 10.1128/MCB.22.8.2777-2787.2002 }}</ref> ande
* [[Zinc finger and BTB domain-containing protein 16|ZBTB16]].<ref name="pmid12460926">{{cite journal | vauthors = Puccetti E, Obradovic D, Beissert T, Bianchini A, Washburn B, Chiaradonna F, Boehrer S, Hoelzer D, Ottmann OG, Pelicci PG, Nervi C, Ruthardt M | title = AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor | journal = Cancer Res. | volume = 62 | issue = 23 | pages = 7050–8 | date = December 2002 | pmid = 12460926 | doi = }}</ref><ref name="pmid11719366">{{cite journal | vauthors = Ward JO, McConnell MJ, Carlile GW, Pandolfi PP, Licht JD, Freedman LP | title = The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D(3) receptor | journal = Blood | volume = 98 | issue = 12 | pages = 3290–300 | date = December 2001 | pmid = 11719366 | doi = 10.1182/blood.V98.12.3290 }}</ref>
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== Notas ==
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