CD45: Diferenzas entre revisións

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[[Ficheiro:Protein PTPRC PDB 1ygr.png|miniatura|dereita|Modelo do PTPRC (baseado no PDB 1ygr).]]
O '''CD45''' ([[cluster de diferenciación|''cluster'' de diferenciación]]), chamado inicialmente '''antíxeno común leucocitario''', e chamado agora '''PTPRC''' (''Protein Tyrosine Phospatase, Receptor type, C'', proteína tirosina fosfatase, tipo receptor, C) é un [[encima]] que se encontra na superficie de células [[hematopoético|hematopoéticas]], que nos humanos está codificado no [[xene]] PTPRC do [[cromosoma 1]].<ref name="pmid2169617">{{Cita publicación periódica | author = Kaplan R, Morse B, Huebner K, ''et al'' | title = Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 87 | issue = 18 | pages = 7000–4 | year = 1990 | pmid = 2169617 | pmc = 54670 | doi = 10.1073/pnas.87.18.7000| url = http://www.pnas.org/cgi/pmidlookup?view=long&pmid=2169617 | issn =}}</ref><ref name="entrez">{{citeCita web | title = Entrez Gene: PTPRC protein tyrosine phosphatase, receptor type, C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5788| accessdate = }}</ref>
 
== Función ==
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* {{Cita publicación periódica | author=Stanton T, Boxall S, Bennett A, ''et al.'' |title=CD45 variant alleles: possibly increased frequency of a novel exon 4 CD45 polymorphism in HIV seropositive Ugandans. |journal=Immunogenetics |volume=56 |issue= 2 |pages= 107–10 |year= 2004 |pmid= 15057492 |doi= 10.1007/s00251-004-0668-z}}
* {{Cita publicación periódica | author=Huntington ND, Tarlinton DM |title=CD45: direct and indirect government of immune regulation. |journal=Immunol. Lett. |volume=94 |issue= 3 |pages= 167–74 |year= 2005 |pmid= 15275963 |doi= 10.1016/j.imlet.2004.05.011}}
* {{citeCita web | url = http://www.bio.davidson.edu/courses/immunology/Students/spring2006/Jameson/CD45.html | title = CD45 | author = Jameson R | year = 2006 | work = Immunology course for undergraduates | publisher = Davidson College | accessdate = 2011-10-24 }}
 
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