Diferenzas entre revisións de «8-Oxoguanina»

== En fluídos corporais ==
 
O incremento das concentracións de 8-oxoguanina nos [[fluído corporal|fluídos corporais]] asociouse cun incremento do risco de [[mutaxénese]] e [[carcinoxénese]].<ref>{{cite journal|last1=Kasai|first1=H|title=Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis.|journal=Mutation research|date=December 1997|volume=387|issue=3|pages=147–63|pmid=9439711|doi=10.1016/s1383-5742(97)00035-5}}</ref><ref>{{cite journal|last1=Halliwell|first1=B|title=Can oxidative DNA damage be used as a biomarker of cancer risk in humans? Problems, resolutions and preliminary results from nutritional supplementation studies.|journal=Free Radical Research|date=December 1998|volume=29|issue=6|pages=469–86|pmid=10098453|doi=10.1080/10715769800300531}}</ref>
 
Os ensaios doncon 8-oxoguanina deben facerse con moito coidado debido á facilidade coa quedque pode ser oxidada durante a extracción e os procedementos do ensaio.<ref>{{cite journal |last1=Ravanat |first1=JL| last2=Douki |first2=T |last3=Duez |first3=P |last4=Gremaud |first4=E |last5=Herbert |first5=K |last6=Hofer |first6=T |last7=Lasserre |first7=L |last8=Saint-Pierre |first8=C |last9=Favier |first9=A |last10=Cadet |first10=J |title=Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up |journal=Carcinogenesis |date=November 2002 |volume=23 |issue=11 |pages=1911–8 |pmid=12419840 |doi=10.1093/carcin/23.11.1911}}</ref>
 
== Notas ==
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