Interferón gamma: Diferenzas entre revisións

The IFNγ [[monomer]] consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region.<ref name="pmid1902591">{{cite journal | author = Ealick SE, Cook WJ, Vijay-Kumar S, Carson M, Nagabhushan TL, Trotta PP, Bugg CE | title = Three-dimensional structure of recombinant human interferon-gamma | journal = Science | volume = 252 | issue = 5006 | pages = 698–702 | date = May 1991 | pmid = 1902591 | doi = 10.1126/science.1902591 | url = }}</ref><ref name=PDB_1FG9> {{PDB|1FG9}} ; Thiel DJ, le Du MH, Walter RL, D'Arcy A, Chène C, Fountoulakis M, Garotta G, Winkler FK, Ealick SE (September 2000). "Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex". Structure 8 (9): 927–36. doi:10.1016/S0969-2126(00)00184-2. PMID 10986460. </ref> This is shown in the structural models below. The α-helices in the core of the structure are numbered 1 to 6.