Interferón gamma: Diferenzas entre revisións

The IFNγ [[monomer]] consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region.<ref name="pmid1902591">{{cite journal | author = Ealick SE, Cook WJ, Vijay-Kumar S, Carson M, Nagabhushan TL, Trotta PP, Bugg CE | title = Three-dimensional structure of recombinant human interferon-gamma | journal = Science | volume = 252 | issue = 5006 | pages = 698–702 | date = May 1991 | pmid = 1902591 | doi = 10.1126/science.1902591 | url = }}</ref><ref> {{PDB|1FG9}} ; Thiel DJ, le Du MH, Walter RL, D'Arcy A, Chène C, Fountoulakis M, Garotta G, Winkler FK, Ealick SE (September 2000). name="PDB_1FG9Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex". Structure 8 (9): 927–36. doi:10.1016/S0969-2126(00)00184-2. PMID 10986460. </ref> This is shown in the structural models below. The α-helices in the core of the structure are numbered 1 to 6.