[[ProteinAs aggregation]]enfermidades diseasesde suchagregación asde proteínas como a [[Alzheimer'senfermidade Diseasede Alzheimer]] ande a de [[Huntington'senfermidade Diseasede Huntington|Huntington]] ande as enfermidades [[prionprión]]icas diseasescomo such asa [[bovineencefalopatía spongiformesponxiforme encephalopathybovina]] canpoden beser bettermellor understoodcomprendidas by constructingconstruíndo (ande reconstructingreconstruíndo) [[diseasemodelo modelde enfermidade|modelos de enfermidadesl]]s. ThisIsto isfaise donecausando bya causingenfermidade theen diseaseanimais inde laboratory animalslaboratorio, forpor example,exemplo byadministrando administering aunha [[toxintoxina]], suchcomo asa [[MPTP]] toque causecausa Parkinson'sa disease[[enfermidade de Parkinson]], orou por medio throughde [[geneticenxeñaría engineeringxenética|geneticmanipulación manipulationxenética]].<ref name="park">{{cite journal|pmid=15503155|title=Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP|url=http://www.ncbi.nlm.nih.gov/pubmed/15503155|doi=10.1007/s00441-004-0938-y | volume=318|issue=1|date=October 2004|journal=Cell Tissue Res.|pages=215–224|author=Schober A}}</ref><ref name="ko">{{cite web|url=http://www.sigmaaldrich.com/life-science/learning-center/biofiles/biofiles-5-6/tp53-knockout-rat.html|title=Tp53 Knockout Rat|publisher=Cancer|accessdate=2010-12-18}}</ref>
A [[Proteinpredición structureda predictionestrura de proteínas]] isé un anovo newmodo wayde tocrear createmodelos diseasede modelsenfermidades, whichque maypoden avoidevitar theo useuso ofde animalsanimais.<ref name="bit">{{cite web|url=http://www.bit-tech.net/hardware/graphics/2009/06/15/what-is-folding-and-why-does-it-matter/|title=Feature - What is Folding and Why Does it Matter?|accessdate=December 18, 2010}}</ref>
