Chlamydophila pneumoniae: Diferenzas entre revisións

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| species = ''C. pneumoniae''<ref name="EverettBush1999">{{cite journal|last1=Everett|first1=K. D. E.|last2=Bush|first2=R. M.|last3=Andersen|first3=A. A.|title=Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms|journal=International Journal of Systematic Bacteriology|volume=49|issue=2|year=1999|pages=415–440|issn=0020-7713|doi=10.1099/00207713-49-2-415|pmid=10319462}}</ref>
}}
[[Ficheiro:Chlamydia pneumoniae.jpg|miniatura|Micrografía de ''Ch. pneumoniae'' nunha célula epitelial nun caso de bronquite aguda: 1 - epiteliocito infectado, 2 - epiteliocito non infectado, 3 - corpos de inclusión clamidiais na célula, 4 - núcleo celular.]]
'''''Chlamydophila pneumoniae''''' é unha especie de [[bacteria]]s da familia das [[clamidiáceas]], que é un [[parasito intracelular obrigado]]<ref>{{MeshName|Chlamydophila+pneumoniae}}</ref> que infecta a humanos e é unha das causa importante de [[pneumonía]]s. Coñecíase ao principio como o axente respiratorio agudo de [[Taiwán]] (TWAR) polos nomes dos dous illados orixinais, o illado Taiwán (TW-183) e o illado respiratorio agudo denominado AR-39.<ref>http://pathmicro.med.sc.edu/mayer/chlamyd.htm</ref> Ata hai poucos anos, o nome da especie era '''''Chlamydia pneumoniae''''', e ese nome segue usándose como un nome alternativo nalgunhas fontes.<ref name="urlwww.ncbi.nlm.nih.gov">{{cite web |url=http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83558&lvl=3&lin=f&keep=1&srchmode=1&unlock |title=www.ncbi.nlm.nih.gov |format= |work= |accessdate=2009-01-27}}</ref> Nalgúns casos, para evitar a confusión, danse os dous nomes (téñase en conta que a creación do xénero ''[[Chlamydophila]]'', ao separar algunhas especies de ''[[Chlamydia]]'', foi e é controvertido<ref name="urlwww.ncbi.nlm.nih.gov">{{cite web | url = http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=1113537&lvl=3&lin=f&keep=1&srchmode=1&unlock | title = Chlamydia/Chlamydophila group | work = NCBI taxonomy database | publisher = National Center for Biotechnology Information, U.S. National Library of Medicine | accessdate = 2013-03-26 | quote= Dada a natureza contenciosa deste asunto, a Base de Datos Taxonómica do NCBI mantén os nomes dos dous xéneros para o uso dos que envíen traballos.}}</ref>
 
'''''Chlamydophila pneumoniae''''' é unha especie de [[bacteria]]s da familia das [[clamidiáceas]], que é un [[parasito intracelular obrigado]]<ref>{{MeshName| - Chlamydophila+pneumoniae}} [http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?mode=&term=Chlamydophila+pneumoniae]</ref> que infecta a humanos e é unha das causa importante de [[pneumonía]]s. Coñecíase ao principio como o axente respiratorio agudo de [[Taiwán]] (TWAR) polos nomes dos dous illados orixinais, o illado Taiwán (TW-183) e o illado respiratorio agudo denominado AR-39.<ref>http://pathmicro.med.sc.edu/mayer/chlamyd.htm</ref> Ata hai poucos anos, o nome da especie era '''''Chlamydia pneumoniae''''', e ese nome segue usándose como un nome alternativo nalgunhas fontes.<ref name="urlwww.ncbi.nlm.nih.gov">{{cite web |url=http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83558&lvl=3&lin=f&keep=1&srchmode=1&unlock |title=www.ncbi.nlm.nih.gov |format= |work= |accessdate=2009-01-27}}</ref> Nalgúns casos, para evitar a confusión, danse os dous nomes (téñase en conta que a creación do xénero ''[[Chlamydophila]]'', ao separar algunhas especies de ''[[Chlamydia]]'', foi e é controvertido<ref name="urlwww.ncbi.nlm.nih.gov">{{cite web | url = http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=1113537&lvl=3&lin=f&keep=1&srchmode=1&unlock | title = Chlamydia/Chlamydophila group | work = NCBI taxonomy database | publisher = National Center for Biotechnology Information, U.S. National Library of Medicine | accessdate = 2013-03-26 | quote= Dada a natureza contenciosa deste asunto, a Base de Datos Taxonómica do NCBI mantén os nomes dos dous xéneros para o uso dos que envíen traballos.}}</ref>
).<ref name="pmid18218130">{{cite journal |author=Appelt DM, Roupas MR, Way DS, ''et al.'' |title=Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae |journal=BMC Neurosci |volume=9 |issue= |pages=13 |year=2008 |pmid=18218130 |pmc=2266938 |doi=10.1186/1471-2202-9-13 |url=http://www.biomedcentral.com/1471-2202/9/13}}</ref>
 
''C. pneumoniae'' hasten aun complexciclo lifede cyclevida andcomplexo muste infectdebe anotherinfectar cella tooutra [[reproduction|reproduce]];célula para thusrproducirse, itpolo isque classifiedé asun anparasito [[Obligateintracelular intracellularobrigado. parasite|obligateO intracellularsecuencia pathogen]].completa The fulldo [[genomexenoma]] sequence forde ''C. pneumoniae'' waspublicouse published inen 1999. ItTamén alsopode infectsinfectar ande causescausar diseaseenfermidades innos [[koalacoala]]s, emeralden treecertas boas[[boa]]s (''Corallus caninus''), [[iguana]]s, [[chameleoncameleón]]s, frogsras, ande turtlestartarugas.
 
TheO firstprimeiro knowncaso casecoñecido ofde infectioninfección withpor ''C. pneumoniae'' wasfoi aun casecaso ofde [[sinusitissinusite]] inen [[TaiwanTaiwán]]. ThisEsta atypicalbacteria bacteriumxeralmente commonly causescausa [[pharyngitisfarinxite]], [[bronchitisbronquite]] ande [[atypicalpneumonía pneumoniaatípica]],<ref>Lang, B. R., ''Chlamydia pneumonia'' as a differential diagnosis? Follow-up to a case report on progressive pneumonitis in an adolescent, ''Patient Care'', Sept. 15, 1991</ref> mainly in elderly and debilitated patients, but in healthy adults, also.<ref>Little, Linda, Elusive pneumonia strain frustrates many clinicians, ''Medical Tribune'', p. 6, September 19, 1991</ref>
[[File:Chlamydia pneumoniae.jpg|thumb|Micrograph of''Chlamydophila'' (''Chlamydia'') ''pneumoniae'' in an epithelial cell in acute bronchitis: 1 - infected epitheliocyte, 2 - uninfected epitheliocytes, 3 - chlamydial inclusion bodies in cell, 4 - cell nuclei]]
 
== Ciclo de vida e método de infección ==
 
[[ImageFicheiro:Chlamydophila pneumoniae.jpg|thumbminiatura|rightdereita|200px|LifeCiclo cyclede ofvidad de ''ChlamydophilaCh. pneumoniae''.]]
 
''Chlamydophila pneumoniae'' is a small gram negative bacterium (0.2 to 1 [[micrometre|μm]]) that undergoes several transformations during its life cycle. It exists as an [[elementary body]] (EB) between [[Host (biology)|host]]s. The EB is not biologically active, but is resistant to [[Natural environment|environment]]al stresses and can survive outside a host for a limited time. The EB travels from an [[infection|infected]] person to the [[lung]]s of an uninfected person in small [[droplet]]s and is responsible for infection. Once in the lungs, the EB is taken up by [[cell (biology)|cell]]s in a pouch called an [[endosome]] by a process called [[phagocytosis]]. However, the EB is not destroyed by fusion with [[lysosome]]s, as is typical for phagocytosed material. Instead, it transforms into a [[reticulate body]] and begins to replicate within the endosome. The reticulate bodies must use some of the host's cellular metabolism to complete its replication. The reticulate bodies then convert back to elementary bodies and are released back into the lung, often after causing the death of the host cell. The EBs are thereafter able to infect new cells, either in the same [[organism]] or in a new host. Thus, the life cycle of ''C. pneumoniae'' is divided between the elementary body, which is able to infect new hosts but can not replicate, and the reticulate body, which replicates but is not able to cause new infection.