Secuenciación do ADN: Diferenzas entre revisións

DNA sequencing methods currently under development include labeling the DNA polymerase,<ref>{{cite web|url=http://visigenbio.com/technology_overview.html|title=VisiGen Biotechnologies Inc. – Technology Overview |publisher=Visigenbio.com |date= |accessdate=2009-11-15}}</ref> reading the sequence as a DNA strand transits through [[nanopore sequencing|nanopores]],<ref>{{cite web|url=http://mcb.harvard.edu/branton/index.htm |title=The Harvard Nanopore Group |publisher=Mcb.harvard.edu|date= |accessdate=2009-11-15}}</ref><ref name="Physorg">{{cite web |url=http://www.physorg.com/news157378086.html |title=Nanopore Sequencing Could Slash DNA Analysis Costs |work= |accessdate=}}</ref> and microscopy-based techniques, such as [[Atomic force microscope|atomic force microscopy]] or [[Transmission electron microscopy DNA sequencing|transmission electron microscopy]] that are used to identify the positions of individual nucleotides within long DNA fragments (&gt;5,000 bp) by nucleotide labeling with heavier elements (e.g., halogens) for visual detection and recording.<ref>{{ US patent reference20060029957, ZS Genetics, "Systems and methods of analyzing nucleic acid polymers and related components", issued 2005-07-14</ref><ref>{{cite journal |author=Xu M, Fujita D, Hanagata N |title=Perspectives and challenges of emerging single-molecule DNA sequencing technologies|journal=Small |volume=5 |issue=23 |pages=2638–49 |year=2009 |month=December |pmid=19904762 |doi=10.1002/smll.200900976 |url=}}</ref>