Célula de Clara: Diferenzas entre revisións

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Miguelferig (conversa | contribucións)
Miguelferig (conversa | contribucións)
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==Enfermidades==
ClaraAs cellscélulas containde Clara conteñen [[Tryptasetriptase clara]], whichque isse believedpensa toque beé responsibleresponsable forde cleavingcortar thea molécula de [[hemagglutininhemaglutinina]] surfacepresente proteinna superficie do virus ofda [[influenza Agripe]] virusA, therebyo activatingque ito andactiva causinge thecausa symptomsos ofsíntomas fluda gripe. <ref name="pmid9707539">{{cite journal |author=Taubenberger JK |title=Influenza virus hemagglutinin cleavage into HA1, HA2: No laughing matter |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue=17 |pages=9713–5 |year=1998 |month=August |pmid=9707539 |pmc=33880 |doi= 10.1073/pnas.95.17.9713|url=http://www.pnas.org/cgi/pmidlookup?view=long&pmid=9707539}}</ref> WhenNos theratos, [[Chromosomecando 11a openproteína reading frame 73|[[l7Rn6]] proteiné isdestruída, disrupted in mice,os theseanimais micemostran displaysíntomnas severede [[emphysemaenfisema]] atgrave birthao asnaceren acomo resultresultado ofda disorganizationdesorganización of thedo [[Golgiaparato apparatusde Golgi]] ande formationa offormación aberrantde vesicularestruturas structuresvesiculares withinaberrantes clarano cellsinterior das células de Clara. <ref name="pmid16157679">{{cite journal | author = Fernández-Valdivia R, Zhang Y, Pai S, Metzker ML, Schumacher A | title = l7Rn6 Encodes a Novel Protein Required for Clara Cell Function in Mouse Lung Development | journal = Genetics | volume = 172 | issue = 1 | pages = 389–99 | year = 2006 | month = January | pmid = 16157679 | pmc = 1456166 | doi = 10.1534/genetics.105.048736 | url = }}</ref>
 
==Notas==