Diferenzas entre revisións de «Queratán sulfato»

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O '''queratán sulfato''' ou '''sulfato de queratán''' (KS) é un tipo de [[glicosaminoglicano]] (carbohidratos estruturais) sulfatado, que se encontra especialmente na [[córnea]], [[cartilaxe]], e [[óso]]. Sintetízase tamén no [[sistema nervioso central]], onde participa no desenvolvemento neural <ref name="pmid9087531">{{cite journal |author=Miller B, Sheppard AM, Pearlman AL |title=Developmental expression of keratan sulfate-like immunoreactivity distinguishes thalamic nuclei and cortical domains |journal=[[J. Comp. Neurol.]] |volume=380 |issue=4 |pages=533–52 |year=1997 |month=April |pmid=9087531|doi=10.1002/(SICI)1096-9861(19970421)380:4<533::AID-CNE9>3.0.CO;2-2}}</ref> e na cicatrización glial dos danos neurais <ref name="pmid17185507">{{cite journal |author=Zhang H, Uchimura K, Kadomatsu K |title=Brain keratan sulfate and glial scar formation |journal=[[Ann. N. Y. Acad. Sci.]] |volume=1086 |issue= |pages=81–90 |year=2006 |month=November |pmid=17185507 |doi=10.1196/annals.1377.014 |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0077-8923&date=2006&volume=1086&spage=81}}</ref>. Os queratán sulfatos son moléculas grandes e moi hidratadas, que actúan nas articulacións como amortecendo os golpes mecánicos.
'''Keratan sulfate''' (KS), also called '''keratosulfate''', is any of several [[Sulfuric acid|sulfated]] [[glycosaminoglycans]] (structural carbohydrates) that have been found especially in the [[cornea]], [[cartilage]], and [[bone]]. It is also synthesized in the [[central nervous system]] where it participates both in [[neural development|development]]<!--
 
--><ref name="pmid9087531">{{cite journal |author=Miller B, Sheppard AM, Pearlman AL |title=Developmental expression of keratan sulfate-like immunoreactivity distinguishes thalamic nuclei and cortical domains |journal=[[J. Comp. Neurol.]] |volume=380 |issue=4 |pages=533–52 |year=1997 |month=April |pmid=9087531|doi=10.1002/(SICI)1096-9861(19970421)380:4<533::AID-CNE9>3.0.CO;2-2}}</ref><!--
 
--> and in the [[glial scar]] formation following an injury.<!--
 
--><ref name="pmid17185507">{{cite journal |author=Zhang H, Uchimura K, Kadomatsu K |title=Brain keratan sulfate and glial scar formation |journal=[[Ann. N. Y. Acad. Sci.]] |volume=1086 |issue= |pages=81–90 |year=2006 |month=November |pmid=17185507 |doi=10.1196/annals.1377.014 |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0077-8923&date=2006&volume=1086&spage=81}}</ref><!--
 
--> Keratan sulfates are large, highly hydrated molecules which in joints can act as a cushion to absorb [[shock (mechanics)|mechanical shock]].
 
==Estrutura do queratán sulfato==
 
[[ca:Queratan sulfat]]
[[en:Keratan sulphatesulfate]]
[[fr:Sulfate de kératane]]
[[ja:ケラタン硫酸]]
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